Original Article by DR. PETER AND GINGER BREGGIN
Dr. Peter Breggin has gone against the grain in offering his expertise on the “new fad” of people taking Methylene Blue. (e.x. RFK Jr) He posted this article on his Substack.
The Potential Horrors of Methylene Blue as a Health Aid
To get a sense of all the potential adverse effects of methylene, just look up all the adverse effects of all the antidepressants, all the stimulants, all the antipsychotic drugs, and the main anti-Parkinsonian drugs. Methylene blue is a witch’s brew of neurotoxins. It jacks up the output of serotonin, dopamine, and norepinephrine in the brain, and eventually, the brain will react by jacking down all three neurotransmitters. That’s probably worse than most witch’s brews.
Add this pharmacological fact that there is no such thing as a drug that affects only one, two, or three neurotransmitters because every neurotransmitter system lives in a complex balance with all the others in the brain. Soon, other neurotransmitters will compensate for or be injured by original intruders. So, methylene blue will get you coming and going. It would be sold as “the most potent all-purpose psychiatric drug (neurotoxin) of all,” but there’s no money in it.
But I hope I haven’t given any ideas to the pharmaceutical companies. They could tweak it to get a patent and then push it as they have done with other drugs as “modulating”multiple neurotransmitters.
In general, drugs are neurotoxins that can only impair the brain. They “work” by dulling the brain or giving it an artificial high, grossly interfering with normal function. The exceptions are genuine documented biological deficiencies of a naturally occurring substance already present in the brain, usually hormones like estrogen, testosterone, or thyroid, which Dr. Vliet addresses.
There are no known neurotransmitter deficiencies in the brain that are being corrected by psychiatric drugs—the brain, mind, and spirit are too complex and subtle for that. And anyway, unlike correctly used hormones, all psychiatric drugs are neurotoxins, poisonous to overall brain function. This is a subject upon which I have authored multiple books and scientific articles, including Medication Madness and Psychiatric Drug Withdrawal.
Good drugs are regularly forced out by bad ones that often attack our very spiritual nature while engorging the wealth and power of the elites.
Methylthioninium chloride, commonly called methylene blue, is a salt used as a dye and as a medication. As a medication, it is mainly used to treat methemoglobinemia. It has previously been used for treating cyanide poisoning and urinary tract infections, but this use is no longer recommended.
Methylene blue is typically given by injection into a vein. Common side effects include headache, nausea, and vomiting.
Methylene blue was first prepared in 1876, by Heinrich Caro. It is on the World Health Organization’s List of Essential Medicines.
Methylene blue increases blood pressure in people with vasoplegic syndrome(redistributive shock), but does not improve delivery of oxygen to tissues or decrease mortality.
Methylene blue has been used in calcium channel blocker toxicity as a possible rescue therapy for distributive shock unresponsive to first line agents. Limited to case reports, a 2024 review found low-quality evidence that methylene blue may reduce short-term mortality, duration of the need for vasopressors, and length of hospital stay.

Methylene blue has been described as “the first fully synthetic drug used in medicine”. Methylene blue was first prepared in 1876 by German chemist Heinrich Caro.
Its use in the treatment of malaria was pioneered by Paul Guttmann and Paul Ehrlich in 1891. During this period before World War I, researchers like Ehrlich believed that drugs and dyes worked in the same way, by preferentially staining pathogens and possibly harming them. Changing the cell membrane of pathogens is in fact how various drugs work, so the theory was partially correct, although far from complete. Methylene blue continued to be used in World War II, where it was not well-liked by soldiers, who observed, “Even at the loo, we see, we pee, navy blue.”
It was discovered to be an antidote to carbon monoxide poisoning and cyanide poisoning in 1933 by Matilda Brooks.
Methylene blue was the original prototype or lead compound for the design of many antimalarials including chloroquine, antihistamines, and antipsychotics including chlorpromazine.



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